Abstract

M. Reza Shishehbore

DOI : http://dx.doi.org/10.13005/ojc/290229

In this study, the electro-oxidation of vitamin B9 and vitamin B12 and their mixture has been studied by modified multi-wall carbon nanotubes paste electrode of a synthetic hydroquinone derivative using cyclic voltammetry, chronoamperometry and differential pulse voltammetry. The cyclic voltammetric responses of the modified electrode showed the characteristic shape typical of an ECcat process. The obtained catalytic peak current by differential pulse voltammetry was linearly dependent on the vitamin B9 on concentration range 1.5-135.3 μM with limit of detection 0.2 μM. The proposed method was successfully applied for the determination of vitamin B9 and vitamin B12 in pharmaceutical samples satisfactorily.

Vitamin B9 and B12; Simultaneous determination; Multi-wall carbon nanotubes

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