Abstract

Khalid J. Al-Adilee, Shaimaa M. Eassa and  Haitham K. Dakhil

DOI : http://dx.doi.org/10.13005/ojc/320518

The azo reagent 2-((E)-(1H-benzo[d]imidazol2-yl)diazenyl)-5-((E)-benzyl ideneimino)phenol(BIADPI) was prepared and examined  by using  element  analysis(C.H.N.),UV-Vis., Mass spectrum, ¹H-NMR spectrum and infrared spectra.  A sensitive and selective  spectrophotometric method is  proposed for the rapid determination of iron (III) and chromium(III) using (BIADPI) , as spectrophotometer reagent. The reaction between this reagent with chromium(III) and iron (III) is instantaneous at (586,536) nm (λ_max) and pH=(7.5,4) to form perpul complexes having  a mole ratio 1 : 2 (metal : ligand) for Cr (III)  and Fe(III) the absorbance  remains stable  for over 24 hours. Beer's law is obeyed in the rang of (1-14) μg.ml^-1 and (1-21) μg.ml^-1with molar absorptivity (Є) = (7.768x10⁵ , 9.3575x10⁵) L.mol^-1.cm^-1 and a detection limit of (0.275-0.14) μg.ml^-1 obtained respectively. The precision and accuracy were obtained to be R.S.D%=(0.9-0.467)%,Re%=(99.1-98.2-)% and E_rel%= (-1.8 - 0.9)%.The method is  successfully  employed  for the  determination of  iron(III) in  Pharmaceutical preparations(Anemiadrugs).The most important interferences were due to Ni(II), Zn(II), Co(II), Cd(II), Cu(II)and Hg(II) and suitable masking  agents were used.

(BIADPI); Determination; Chromium; Iron; Spectrophotometry; Schiff base

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