ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Synthesis of 3-(2'-Hydroxy-3'-Nitro-5'-Methylphenyl)-5-(Aryl/Heteryl) Isoxazolines

S. V. Agarkar and S. B. Borul


Abstract:

The present study deals with the synthesis and characterization of 3-(2'-hydroxy-3'-nitro-5'-methylphenyl)-5-(aryl/heteryl) isoxazolines synthesized from 1-(2'-hydroxy-3'-nitro-5'-methylphenyl)-3-aryl/heteryl-2-propen-1-ones by reaction with hydroxylamine hydrochloride and sodium acetate in ethanol. The structures of synthesized compounds have been established by spectral and elemental analysis.

Keywords:

Isoxazolines; antiinflammatory; antimicrobial activity

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