ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

A Validation of an Hplc Method for the Determination of Ibuprofen in Presence of its Degradation Products

Rym Guelmami Chayeh1, M. Ben Salah1 and Rachid Chemli1


Abstract:

A rapid high performance liquid chromatographic method was developed to dose the ibuprofen in the presence of its degradations products coming from a stress treatments under different conditions of degradation (acidic, alkaline and oxidant).Its possible to dose this therapeutic molecule in presence of its degradations products if we use a C18 (SUPELCOSILTMLC-18-DB) phase column with a mobile phase ac

Keywords:

ibuprofen; HPLC; validation

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