ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
     FacebookTwitterLinkedinMendeley

Abstract

Study of Mesoionic Compounds: Synthesis and Pharmacological Evaluation of Several 2-[{(4-Substituted-1-sulphonyl) Sydnon-3-yl}]-1,3,4-thiadiazino(6,5-b)indoles as Antimicrobial, Insecticidal and Antihelmintic Agents

Ranjana Dubey1, Nidhi Chaudhary2, Ravindra Kumar3 and Hament Panwar3*

DOI : http://dx.doi.org/10.13005/ojc/300134


Abstract:

In the present study several novel 2-[{(4-Substituted-1-sulphonyl)sydnon-3-yl}]-1,3,4-thiadiazino(6,5-b) indoles [4a-f] synthesised from 2-amino-1,3,4-thiadiazino (6,5-b) indole. Structures of the synthesized substituted indoles were characterized by IR, 1H-NMR, Mass and elemental analysis (C, H, N). Synthesised indole derivatives were screened for antimicrobial, insecticidal and anthelmintic activities. Compound 4a displayed significant biological spectrum.

Keywords:

Antimicobial; insecticidal; antihelmintic; sydnones; indoles.

[ View HTML Full Text]

Back to TOC