ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
     FacebookTwitterLinkedinMendeley

Abstract

Microwave Assisted Synthesis and Antimicrobial Activity of 7-Chloro-6-Fluoro-2-(Substituted Aromatic Sulphonyl Hydrazino) Benzothiazoles

S. M. Hipparagi1, U. K. Majumder2, B. Parikshit1 M. Geethavani1 and V. Suresh Kumar1


Abstract:

In the present work prepared 7-chloro-6-fluoro-benzothiazole-2-ylamine(P) from 3-chloro-4-fluoro-phenylamine. 7-chloro-6-fluoro-benzothiazole-2-ylamine on treatment with hydrazine hydrate in microwave oven for 6minutes to get 7-chloro-6-fluoro-benzothiazol-2-yl-hydrazine(PB) which on treatment with different substituted aromatic sulphonyl compounds yields the title compounds(PB1-9). Various compound and their derivatives were prepared and conformed by IR, NMR and Mass spectra. Antimicrobial study shown that synthesized compounds have moderate activity.

Keywords:

Benzothiazole; Substituted sulphonyl chlorides; antimicrobial activity

[ View HTML Full Text]

Back to TOC