Abstract
Microwave Assisted Synthesis of Some 2,5-Disubstituted 1,3,4-Oxadiazoles and Their Antimicrobial Activities
Anurag Khatkar*, U.K. Singh, S.K. Dewan1 Jagbir Gagoria2 and Sarita3
Abstract:
A variety of 2,5 – disubstituted 1,3,4 –oxadiazoles have been synthesized from Isoniazid and the corresponding aromatic acids both in the presence and in the absence of Mont morillonite K-10 clay catalyst. The synthesized compounds were screened for their antimicrobial activities. Better results were obtained in the presence of the catalysts.
Keywords:1;3;4-oxadiazole; microwave irradiation; antimicrobial activity
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