ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

A New Method for Synthesis of 2,4,5-Triaryl-1H-Imidazole Derivatives Using SiO2-NaHSO4 under Solvent-free Conditions

Farhad Hatamjafari and Hadiseh Khojastehkouhi*

DOI : http://dx.doi.org/10.13005/ojc/300143


Abstract:

A mixture of benzyl, aromatic aldehyde and ammonium acetate in presence of SiO2-NaHSO4 under solvent-free condition were converted to 2,4,5-Triaryl-1H-Imidazoles. The short reaction time, cleaner reaction, and easy workup make this protocol practical and economically attractive.

Keywords:

Imidazoles; Solvent-free; Multicomponent reactions; SiO2-NaHSO

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