Abstract
Panantoprazole sodium sesquihydrate complexes: Synthesis, characterization, potentiometric determination and DNA interaction
W. H. Hegazy*1, Y. M. Issa2 , W. N. El-Sayed1,3, H. I. Ahmed1
DOI : http://dx.doi.org/10.13005/ojc/320234
Abstract:
The synthesis and characterization of solid complexes for pantoprazole sodium sesquihydrate with Cd(II), Hg(II) and Zn(II) metals in molar ratios M:L = 1:2 was studied. The complexes are stable in the solid state and are soluble only in DMF and DMSO. The metal complexes were characterized by elemental analysis, molar conductivity measurements, magnetic susceptibility, UV spectrophotometry, IR, Mass spectra, TGA/DTG analysis. Potentiometric measurements for these metal complexes were studied.
Keywords:Pantoprazole; complexes; potentiometry; Proton Pump Inhibitors; DNA interaction
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