Abstract

Lamia A. Al-bedair^1,2

DOI : http://dx.doi.org/10.13005/ojc/320169

Binary and mixed ligand complexes of Zn(II) involving amlodipine drug (A) as a primary ligand and some amino acids (L) as a secondary ligands are investigated. The acidity constants of the ligands were determined and used for determining the stability constants of the complexes formed in 80% (v/v) ethanol-water media under the experimental conditions at 25 ºC , I = 0.10 M (NaNO₃) by using potentiometric technique. The potentiometric data were analysed using the computer program HYPERQUAD. The concentration distribution of the complexes in solution was evaluated.

Amlodipine; Amino acids; Stability constant; potentiometric

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