Abstract

Khlood Saad Abou- Melha

DOI : http://dx.doi.org/10.13005/ojc/310406

VO(II), Ni(II), Pd(II), Pt(IV) and UO₂(II) complexes were prepared using H₅L ligand (C₂₁H₁₅N₉S₂O₃S₂). All the prepared complexes are deliberately discussed using different tools(IR, Uv-Vis, ¹HNMR, ESR ¹³CNMR, TGA, TEM, XRD).The octadentate is the main mod of ligand donation, as a neural or trinegativetowards the metal ion. This is verified using molecular modeling as a theoretical tool assert on the stereo structure of the ligand proposed leads to the donation mod. The structural formulas of the complexes were varied in between four to six coordination no. except the VO(II) complex is five. Most investigated complexes are thermally unstable due to the presence of crystal water occluded the coordinating crystal. All the spin Hamiltonian parameters as well as molecular orbital parameters were calculated for VO(II) complex. XRD patterns were investigated to calculate the particle size of each compound and display their nanosized by distinguish values. TEM scenes are also supporting the XRD data. Finally the biological activities were carried out on different bacteria as well as on fungi. The toxic effect was observed especially with Gram positive bacterium (Bacillus subtilis). Also, the effect on DNA degradation was recorded and display a complete degradation by the use of  Pt(IV) and Pd(II) complexes. Whereas, a partial degradation was observed with Ni(II) and UO₂(II) complexes. But, there is no effect observed with the use of ligand and VO(II) complex.

Thiouracil derivative; SEM; Gamma rays; Spectral; Modeling; Biological

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