Abstract

Ghania Benaiche^1*, Noureddine Belattar², Srecko Trifunnovic³, Nenad Vukovic³, Danijela Todorovic³, Milos Todorovic⁴, Dejan Baskic⁴ and Milena Vukić³.

DOI : http://dx.doi.org/10.13005/ojc/310411

In this study, two known quinolizidine alkaloids which are sparteine and lupanine were isolated from the methanolic extract of the plant CytisusPurgans of Algerian flora by open column chromatography. These two compounds were identified on the basis of their spectral data (GC/MS, IR, MS, ¹H and ¹³C). The anti-tumor activity of the crude methanolic extract of the aerial parts of the plant was also evaluated invitro against human breast cancer (MDA-MB-231) and human lung cancer (A549) cell lines using MTT assay.

Quinolizidine alkaloids; cytisus purgans; Fabaceae; Algerian flora; anti-tumor activity

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