ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

NaBH4/PhCO2H:  An Efficient system for Reductive Amination of Aldehydes

Nima Mohammadi and Davood Setamdideh*

DOI : http://dx.doi.org/10.13005/ojc/310476


Abstract:

NaBH4/PhCO2H system has been used for the reductive amination of a variety of aldehydes with anilines. The reductive amination reactions have been performed within 60-120 min in THF under reflux conditions in high to excellent yields of products (85-95%).

Keywords:

NaBH4; PhCO2H; Reductive amination; Aldehydes; Amines

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