ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Synthesis and Antimicrobial Activity of 2-R 5-oxo 5-H 6 -carbohydrazin 7-phenyl 1,3,4-thiadiazolo-[3,2-a] pyrimidine

Reza Moradivalikboni1*, Yuldashboy Hozhiboevy1, Zabialah Heidarnezhad2

DOI : http://dx.doi.org/10.13005/ojc/290452


Abstract:

The synthesis of 2-R 5-oxo  5-H  6 -carbohydrazin 7-phenyl  1,3,4-thiadiazolo-[3,2-a] pyrimidine is described. This compound exhibits a broad spectrum of antimicrobial action and can be useful in the search for new antimicrobial drugs. Reactions  of 2- R  5 - Oxo  5 - H  6- EthylCarboxilate 7 – phenyl   -1, 3,4 – Thiadiazolo-[3,2-a] pyrimidine   with hydrazine produce  2-R 5-oxo  5-H  6 – carbohydrazin 7-phenyl  1,3,4-thiadiazolo-[3,2-a] pyrimidine. The structures of the compounds obtained are set NMR, 13C, IR- spectroscopy.

Keywords:

pyrimidine;Hydrazine;Synthesis;IR- spectroscopy;NMR;13C

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