Abstract

Mervat M. El-Enany, Salwa E. M. El-Meligie, Nadia A. Abdou and Hala B. El-Nassan

A number of 1,3-diaryl-2-propen-1-ones 1a-e was reacted with semicarbazide HCl and thiosemicarbazide to afford two series of 3,5-diaryl-4,5-dihydropyrazoles 2a-c and 3a,b. Cyclization of 3a,b with 4-bromophenacyl bromide and ethyl chloroacetate afforded 4,5-dihydropyrazolylthiazoles 4a,b and 5a,b. Finally, some of the new compounds were tested for their possible antimicrobial activity.

4,5-dihydropyrazoles; 4;5-dihydropyrazolylthiazoles

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