Synthesis and Characterisation of Tolbutamide Complexes With Mg (II), Ba (II), Mn (II), and Co (II)

Asmi Desnavi And S. A. Iqbal

Department of Chemistry, Saifia College, Bhopal-462 001 India.

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ABSTRACT:

Tolbutamide, 1-Butyl-3 [P-(tolyI sulphonyl)] urea an oral antidiabetic drug forms 2 :1 (L:M) Complexes with Ba (II), Mg (II), Mn (II) and Co (II) ions, as indicated by Conductometric titrations and Jobs method of continuous variation. Analytical results agree with the compositions. (C12H17N2O3S)2 M for Ba (II) and Mg (II), while (C12H17N2O3S)2 M. 2H2O for Mn.(II) and Co (II) respectively, Structures assigned to the camplexes are supported by I. R. Spectral data.

KEYWORDS:

Characterisation; Tolbutamide; Ba (II); Mn