Studies on Amoebicidal Agents : II. Synthesis And Amoebicidal Activity of Toluene-2:4-Bis-Sulfon-N-Anilides

A. M. Badawi¹, A. A. Harfoush¹, A. Shalaby², T. M. Abdel-Rahman²

¹Center of Science and Mathematics, Taif, Saudi Arabia. ²Chemistry Department, Faculty of Science, Ain Shams University, Cairo, Egypt.

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ABSTRACT:

Several toluene-2 : 4-bis-suIfon-N-anilides were prepared and evaluated for amoebicidal activity. The bis-sulfon-N-methylanilide of 2-amino pyridine, 6-sulfamoyl saccharines and bis-sulfonyl azide showed significant activity against Entamoeba histolytica.

KEYWORDS:

Amoebicidal; Agents; Toluene-2:4-Bis-Sulfon-N-Anilides