Synthesis of Some Trimellitic Acid Amide Derivatives

A. M. EL-Naggar, A. F. El-Haddad, F. A. Kora, A. M. Gomma and M. A. Abou El-Abbas

Chemistry Department, Faculty of Science. Al-Azhar University, Nasr-City, Cairo Egypt.

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ABSTRACT:

Some Trimeliitic acid amides (II-XIX) are prepared by condensation of trimellitic anhydride with different substituted aromatic amines in glacial acetic acid. N4 Sulphanitamide* Sulphathiazole, and Sulphaguanidinetrimellitoyl amino acid combinations (XX-XXIII) are also synthesized and reported. Some of the synthisied compounds are found to posses antimicrobial properties towards a number of microorganisms.

KEYWORDS:

Trimellitic; Amide; Derivatives