Synthesis of Some New Nitrogen Heterocyclics as Potential Anti – Cancer and Anti – Hiv Agents

S. D. Bhardwaj and V. S. Jolly

Cancer Hospital and Research Institute, Gwalior, Madhya Pradesh India.

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ABSTRACT:

Twelve new pyrazoles have been synthesized by reacting 2,4-diketo -3- (phenyl azo)- pentane, 2,4 -diketo -3- (M-methyl phenylazo) pentane with six acid hydrazides. Synthesis of nine pyrazolone azo dyes has been accompalished by reacting of ethyl -1-(o - carboxyphenylazo) acetoacetate with Nine acid hydrazides. The products have been investigated for their anti-cancer and anti-HIV activities.

KEYWORDS:

Pyrazolone; Synthesized; Hydrazides