Studies on Arylthiophene Heterocycles Part -1 : Synthesis and Biological Activity of Some 2-Aryl/ Arylamino-4- [5-(p-Nitrophenyl)-2-Thienyl)]Thiazoles

Balakrishna Kalluraya; Suresh N. Shetty

Article | Open Access

Studies on Arylthiophene Heterocycles Part -1 : Synthesis and Biological Activity of Some 2-Aryl/ Arylamino-4- [5-(p-Nitrophenyl)-2-Thienyl)]Thiazoles

Balakrishna Kalluraya* and Suresh N. Shetty

Department of Studies in Chemistry, Mangalore University. Mangalagangotri - 574 199 India.

Download this article as:

ABSTRACT:

The preparation of sixteen new 2-aryl/arylamino-4-[5-(p-Nitrophenyl)-2-Thienyl)] thiazoles is described. The new compounds were screened for their antibacterial activity against both Gram-positive and Gram-negativa bacteria. The screening results indicates that compounds carrying the arylamino substituent at the 2-position are more active.

KEYWORDS:

Arylthiophene; Heterocycles;Thiazoles