Synthesis, Characterization and Microbial Activity of Naphthalene Containing 1,3-Thiazines

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1.3 - Thiazine derivatives have been prepared in 60-80% yield by the reaction of various chalcones containing naphthalene moeity with thiourea or diphenyl thiourea in alkaline medium for 3-4 hrs. The same reaction in DMSO-sodium methoxide system was found to be fast and give better yield. These compounds were screened for antifungal and antibacterial activities to various test organisms.

1.3 - Thiazine; chalcones; naphthalene moeity; diphenyl thiourea