Synthesis, and Antimicrobial Activity of Some New Benzylidine Derivatives of 2,3-Diaryl -Thiazolidine-4-Ones

Anjani Solankee; Kishor Kapadia; Pankaj Mistry; Jayesh Patel

Article | Open Access

Synthesis, and Antimicrobial Activity of Some New Benzylidine Derivatives of 2,3-Diaryl -Thiazolidine-4-Ones

Anjani Solankee*, Kishor Kapadia, Pankaj Mistry and Jayesh Patel

Department of Chemistry, B.K.M. Science College, Valsad - 396 001 India.

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ABSTRACT:

Variously substituted N-benzylidine anilines rapidly react with thioglycolic add to give the corresponding 2,3-diaryl-thiazolidine-4-ones. Addition of m-phenoxybenzaldehyde to 2,3-diarylthiazolidine-4-ones resulted in benzylidene derivatives of 2,3-diarylthiazolidine-4-ones. The physical and spectral data of the synthesised compounds were determined. The synthesised compounds were screened for their in vitro antibacterial and anti-HIV activity.

KEYWORDS:

N-benzylidin; 3-diarylthiazolidine-4-ones; Synthesised