Synthesis of 2,4-Diaryl-2,3-Dihydro-1,5-Benzo-Thiazepines as Antibacterial Agents

V. M. Barot¹, S. R. Modi¹ and H. B. Naik²

¹Department of Chemistry, South Gujarat University, Surat, Gujarat India.

²Department of Chemistry, Smt. S. M. P Science College, Talod - 383 215 India.

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ABSTRACT:

o-aminophenol reacts with chalcones (I) in methanol acetic acid to give 3- (2-aminophenylmercapto) -3-aryl propiophenones (II) which immediately undergo cyclisation in situ to give 2,4-diaryl- 2,3-dihydro-1,5-benzo-thiazepines (Ill a).

KEYWORDS:

aminophenylmercapto; propiophenones; immediately cyclisation

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