Synthesis, Antimicrobial and Anticancer Activity of Some New 2,3-Diarylthiazolidine-4-Ones and its 1,1-Dioxide

Anjani Solankee, Kishor Kapadia, Jayesh Patel, Pankaj Mistry and Indrajit Thakor

Department of Chemistry, B.K.M. Science College, Valsad - 396 001 India.

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ABSTRACT:

A series of new 2,3-diaryl thiazolidine-4-ones have been synthesised by condensation of schiff bases with mercapto acetic acid, which on oxidation gives 1,1-dioxides. The schiff bases have been prepared by condensing m-phenoxy benzaldehyde with different aryl amines.The physical and spectral data of the synthesised compounds are determined. The synthesised compounds are screened for their invitro antibacterial and anticancer activity.

KEYWORDS:

Diaryl; thiazolidine; synthesised; m-phenoxy benzaldehyde