Zn[(L)-proline]2: A Novel and Recyclable Catalyst for the Synthesis of 2-Aryl-4(3H)-quinazolinones in Solvent-Free Conditions
¹Department of Chemistry ,Tonekabon Branch, Islamic Azad University, Tonekabon (Iran).
²Islamic Azad University, Tonekabon Branch, Young Researchers Club, Tonekabon (Iran).
Download this article as:
An efficient, solvent-free and facile synthesis of 3-aryl quinazolinones from cyclocondensation of 2-aminobenzamides with aryl aldehydes catalyzed by Zn[(L)-proline]2 in the presence of CuCl2 is described. The salient features of the reaction include good yields , mild reaction conditions , low loading of catalyst , and operational simplicity. The catalyst is reusable and can be applied several times without considerable decrease in the yields and rates of the reactions.
KEYWORDS:2-Aryl quinazolinones; Zn[(L)-proline]2; Solvent-free Conditions; Recyclable Catalyst
