A Convenient Synthesis of Chalcones, Acetylpyrazolines and Aminopyrimidine

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Base catalysed condensation of 2-phenylamino-4-(4¹-chlorophenylamino)-6- (4¹-acetylphenylamino)-s-triazine (5) with different substituted aromatic aldehydes give chalcones (6a-e). These Chalcones (6a-e) on cyclisation with hydrazine hydrate in the presence of glacial acetic acid give acetylpyrazolines (7a-e) and with guanidine hydrochloride in the presence of alkali give aminopyrimidines (8a-e). All the synthesised compounds were characterized by IR,1H NMR and physical data.

Chalcones; acetylpyrazolines; aminopyrimidines; spectral data