Synthesis of Hydrazones Schiff Bases and Microbiological Evaluation of Isonicotinoyl Hydrazide with Different Acetophenone
1Department of Chemistry, Shri Shivaji Science College, Amravati (India).
2Department of Chemistry, S.G.B. Amravati University, Amravati (India).
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A series of hydrazones Schiff bases compounds have been synthesized by reacting isonicotinoyl hydrazide with 2-hydroxy-5-chloro acetophenone, 2-hydroxy-5-methyl acetophenone , 2-hydroxy-5-carboxy acetophenone, 2,5-dihydroxy acetophenone, 2-hydroxy-5-chloro-4-methyl acetophenone, 2-hydroxy-5-chloro-3-nitro acetophenone, 2-hydroxy-5-methyl-3-nitro acetophenone and 2-hydroxy-5-bromo acetophenone. The Schiff bases have been evaluated for the antifungal and antibacterial activities.
KEYWORDS:Schiff bases; Isonicotinoyl hydrazide; Acetophenone; Antibacterial activities
