“On Water” Organic Synthesis: One pot Facile Regioselective Synthesis of (1E,4E)-1,5-bis-aryl-penta-1, 4-dien-3-ones using an Alternative Precursor
Synthesis Research Laboratory, Department of Chemistry, Faculty of Science, University of Guilan, PO Box 41335-1914, Rasht (Iran).
Corresponding Author E-mail: Mahmoodi@guilan.ac.ir
Download this article as:
One-pot synthesis of a series of (1E,4E)-1,5-bis-arylpenta-1,4-dien-3-ones considering as curcumin analogs through the condensation of pentane-2,4-dione with aldehydes in water and base for the fast (5-8min) and high yielding (85- 95%)preparation of dienone systems such as 7a-g are enclosed. The structures of the products were deduced from their elemental analyses and spectroscopic data.
KEYWORDS:On water; One pot; regioselective; (1E,4E)-1,5-bis-aryl-penta-1,4-dien-3-ones
