Silica Sulfuric Acid as a Efficient and Recyclable Solid Acid Catalyst for the One-Pot Synthesis of 2,4,6-Triaylpyridines Under Solvent Free Conditions
Department of Chemistry, Tonekabon Branch, Islamic Azad University, Tonekabon (Iran).
Corresponding author: E-mail: Montazer50@toniau.ac.ir
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An efficient synthesis of 2,4,6-triarylpyridines is achieved via a three-component reaction of acetophenone, aryl aldehydes and ammonium acetate in one-pot under solvent-free conditions. The reaction work-up is very simple and the catalyst can be easily separated from the reaction mixture and reused three times in subsequent reactions.
KEYWORDS:Silica Sulfuric Acid; Solvent-free; 2,4,6-Triarylpyridines; Three-Component
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