Synthesis and Insecticidal Activity of Bis 4, 4′-(2-Substituted Aryl Thiazolidine-4-One) Diphenyl Sulphone

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A series of thiazolidin-4-one have been synthesized by condensation of 4,4'-diamnodiaphenyl sulphone with four different substituted aromatic aldehyde to yield the Schiffsbases. Cyclocondensation of schiff’’s bases with thioglycolic acid afforded bis 4,4'-(2-substituted aryl thiazolidine-4-one)diphenyl sulphone. The structure of newly synthesized compounds were confirmed analytical and spectral (IR & PNMR) data. All these compounds were evaluated for their insecticidalactivity. All four compounds have equipotent Insecticidal activity with the standard drug cypermethrin.

Thiazolidine-4-one; antimicrobial agent