A Fast and New Route to Synthesis of Guanidine Derivatives using Hgcl2 as a Promotor

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A simple and Noval Synthesis of guanidine derivatives is presented in this study. The construction of the Central basic Scaffolds is achieved by the using of HgCl2 as a promoter. The Formation of product of substituted guanidines controlled by amount of reactant. Further a new fast-tract access to N-1(Boc)-N-(2) cyclohexyl-N(3) phenyl-guanidine was developed.

N-BOC-N’ Substituted thiouria N sulphonyl guanidines; Carbodiamide