Synthesis, Characterization and Bioefficacy of Some Cyclic Ketones against Houseflies


Bibhanshu gupta* and A. K. Agarwal
Department of Chemistry, Bareilly College, Bareilly (India).

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ABSTRACT:

Synthesis of some cyclic ketones which include (2E)-3-(2-chloroquinolin-3-yl)-l-phenyl-2-propen-1-one, (2E)-3-(2-Chloro-6-methylquinolin-3-yl)-1-phenyl-2-propen-1-one, (2E)-3-(2,7-Dichloroquinolin-3-yl)-1-phenyl-2-propen-1-one, (2E)-3-(2-Chloro-6-methoxyquinolin-3-yl)-1-phenyl-2-propen-1-one, 2E)-3-(6-Bromo-2-chloroquinolin-3-yl)-1-phenyl-2-propen-1-one were achieved through the condensation of 3-fomylquinolines with acetophenone and 3-acetyl-4-hydroxyquinolin-2(1H)-one with different heterocyclic aldehydes. The synthesized ketones have been screened for insect attractant activities and insecticidal effect against houseflies. All the ketones have shown significant insect attractant properties.

KEYWORDS:

Insect attractant;l ketones; insecticidal effect; 3-fomylquinolines; 3-acetyl-4-hydroxyquinolin-2(1H)-one; acetophenone


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