Synthesis and Antimicrobial Activity of Substituted Benzisoxazoline

A. W. Raut, A. G. Doshi and P. B. Raghuwanshi

Department of Chemistry, Shri Shivaji Science College, Morshi Road. Amravati - 444 602 India.

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ABSTRACT:

Substituted (α-arylimino) ethylbenzene was reacted with DMSO-I₂ - H₂ SO₄ system to give N-substrtuted phenyl benzisoxazoline. All these substituted benzisoxazoline were tested against organism Salmonella typhi! Salmonella paratyphi, Proteus vulgaris, Xanthomonas spp., Fusantm sotanu and Botrytis cinerea. It is found that compound containing bromo and nitro group together are more active than simple benzisoxazoline.

KEYWORDS:

Ethylbenzene; Xanthomonas; benzisoxazoline Botrytis