Synthesis, Characterization and Microbial Activity of Naphthalene Containing 1,3-Thiazine

H. S. Patel and A. P. Patel

Department of Chemistry, Sardar Patel University, Vallabh Vidhyanagar, Gujarat - 388 120 India.

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ABSTRACT:

Naphthalene containing chaicones have been used, to afford 1,3-thiazine derivatives, by reacting with thiourea or diphenyl thiourea in alkaline medium. The yield was found to be 50-70%. Better yield was achieved In DMSO-Sodium methoxide solvent system. These compounds were screened for antifungal and antibacterial activities to various organism.

KEYWORDS:

Naphthalene; Diphenyl; thiourea; alkaline