Synthesis and Antibacterial Activity of 1-H-3-(4′-Chloro-Phen- 1-Yl)-5-Aryl-2-Pyrazolines and Related Compounds

P. A. Mehta; H.B. Naik

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Synthesis and Antibacterial Activity of 1-H-3-(4′-Chloro-Phen- 1-Yl)-5-Aryl-2-Pyrazolines and Related Compounds

P. A. Mehta and H.B. Naik

Department of Chemistry, South Gujrat University, Surat - 395 007 India.

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ABSTRACT:

Some chalcones (1) on condensation with hydrazine hydrate in ethanol gave 1-H-3-(4'-chloro- phen-1'- YL)-5-aryl-2-pyrazolines (2) which were converted to acetyl (3); benzoyl (4) sulphonamide (5); and nitroso (6) derivatives. These varied products have been characterised by spectral studies end screened for anti-bacterial activity.

KEYWORDS:

hydrazine; hydrate; pyrazolines; characterised