A Facile Synthesis, Characterization and Spectral Studies of Some New Thiosemicarbazones

Arista Chaudhaary*, Gunjan Saxena, Shah Nawaz Khan, Arshi Naqvi And D.S. Seth

Department of Chemistry, Chemical Research Laboratory, St. John’s College, Agra - 282 002 (India)

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ABSTRACT:

We propose here rapid and highly efficient synthesis of thiosemicarbazone, a class of compound obtained by condensing substituted thiosemicarbazide with suitable aldehydes or ketones. They belong to a large group of thiourea derivative. Thiosemicarbazones of aromatic aldehydes and ketones possess a broad spectrum of potentially useful chemotherapeutic activities. The structures of substituted thiosemicabazones were characterized by virtue of 1HNMR, I.R Spectroscopy and elemental analysis

KEYWORDS:

Thiosemicarbazones; thiosemicarbazides; aldehydes; ketones