Synthesis and Biological Evaluation of Certain New Pyrazoline Derivatives

Sudheendra, P. Srinivas Rao and R.H. Udupi*

PG Department of Medicinal Chemistry, N. E. T. Pharmacy College, Raichur - 584 103 (India)

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ABSTRACT:

Series of some new Pyrazoline derivatives (6a1-a28) have been synthesized in excellent yields by condensing the hydrazide (4) prepared from Schiff base (3) with different chalcones. The structures of newly synthesized compounds were established on the basis of elemental analysis and spectral data. Few compounds showed significant biological activities.

KEYWORDS:

Biological evaluation; pyrazoline derivatives