Synthesis of Pyrazolyl Triazoles and Thiadiazoles by Conventional and Non-Conventional Methods

S. N. Shelke; C.H. Gill; B. K. Karale

Article | Open Access

Synthesis of Pyrazolyl Triazoles and Thiadiazoles by Conventional and Non-Conventional Methods

S. N. Shelke, C. H. Gill¹ and B. K. Karale*

¹Department of Chemistry, Dr. B. A. M. University, Aurangabad (India) ²Department of Chemistry, S.S.G.M. College, Kopargaon, Ahmednagar- 423 601 (India)

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ABSTRACT:

Compound 1 on treatment with SOCl2 followed by hydrazine hydrate gave acid hydrazide 2. Variously substituted phenyl isothiocyanates with acid hydrazide 2 gave thiosemicarbazides 3. These thiosemicarbazides 3 on treatment with conc. H2SO4 and dil. NaOH gave thiadiazoles 4 and triazoles 5 respectively.

KEYWORDS:

Thiosemicarboazide; Triazole; Thidiazole; Ultrasonucation Microwave irradiation