Preparation and Comparative Studies of Some Substituted 4-Thiazolidinone, 2-Azetidinone and Their 1, 3, 4-Thiadiazole Derivatives

C. R. Kanzariya; M.K. Shah

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Preparation and Comparative Studies of Some Substituted 4-Thiazolidinone, 2-Azetidinone and Their 1, 3, 4-Thiadiazole Derivatives

C.R. Kanzariya and M.K. Shah*

Department of Chemistry, Saurashtra University, Rajkot -360 005 (India)

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ABSTRACT:

Thiadiazole having amino group have been reported to possess insecticidal, herbicidal and pesticidal properties. Other thiadiazoles have been tried as chemotherapeutics and some derivatives showed considerable promise as remedies for irections in the gastral intestinal tract. 2, 5-diamino-1, 3, 4-thiadiazole was formed in 25% yield by the action of phosphorous oxychloride on 1-carbamoyl thiosemicarbazide.

KEYWORDS:

UV; IR spectra; C; H; N analysis; Antibacterial activity