A Facile Generation of Pyranopyrazoles : Synthesis of 2-Amino-3-Cyano-4,5-Dimethyl-7-N-Phenyl-4-(P-Aroylaminophenyl)-Pyrano-[2,3-D]-Pyrazoles

D. N. Nagar; Tushar; Mehta; V. H. Shah

Article | Open Access

A Facile Generation of Pyranopyrazoles : Synthesis of 2-Amino-3-Cyano-4,5-Dimethyl-7-N-Phenyl-4-(P-Aroylaminophenyl)-Pyrano-[2,3-D]-Pyrazoles

D. N. Nagar, Tushar Mehta and V. H. Shah*

Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot- 360 005 (India)

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ABSTRACT:

Starting from 4-(p-aroylaminophenyl) acetophenone (Ia-j), a new synthesis of pyranopyrazoles (II a-j) has been achieved. The structure of newly synthesized compounds was established on the basis of elemental analyses, IR and PMR and mass spectral data. Antimicrobial activity has been performed by using cup-plate method. All the synthesized compounds have shown significant antimicrobial activity.

KEYWORDS:

Pyranopyrazoles; Antimicrobial activity