Evaluation of Isoflavanone as an Antimicrobial Agent from Leaves of Bridelia Retusa (L) Spreng. Veg.

Madhavi Adhav¹*, C. M. Solanki¹, Bhavesh Patel² and Anil Gharia³

¹Department of Botany,P.M.B. Gujarati Science College, Indore- 452 005 (India) ²Department of Microbiology,P.M.B. Gujarati Science College, Indore- 452 005 (India) ³Department of Chemistry, P.M.B. Gujarati Science College, Indore- 452 005 (India)

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ABSTRACT:

Discovery and development of new therapeutic agent is a continuing process in spite of the fact that, at present we have at our command of formidable array of modern drugs, the need to discover and invent new agents is genuine and urgent. A flavonoid was isolated from the benzene fraction of ethanolic leaves extract of Bridelia retusa (Euphorbiaceae) which was identified as Isoflavone by various chemical testing and spectral analysis. The fraction tested has been found to show strong antimicrobial activity against human pathogenic bacteria viz. S. aureus, B. subtilis, E. coli, S. typhi, S. dysenterae and P. aeruginosa. The result correlates the claims of Ayurveda and that of tribals.

KEYWORDS:

Bridelia retusa; Euphorbiaceae; Isoflavone; Antimicrobial