A Convenient one Step Synthesis of 4-Amino-3, 5-Disubstituted-1,2,4-Triazoles

B. N. Sivasankar* and L. Ragunath

¹Department of Chemistry, Government Arts College, Udhagamandalam The Nilgiris-643 002, (India) ²Department of Chemistry, Sri Ramakrishna Engineering College, Coimbatore- 641 022 (India)

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ABSTRACT:

A Convenient one step synthesis of 4-amino-3,5-disubstituted-1,2,4,-triazoles(1-4) have been carried out from hydrazine hydrate and corresponding alkyl or aryl or aryl cyanides in the presence of sulphur dioxide, carbon dioxide or selenium dioxide. The products obtained were characterised by their melting points and infrared spectra. The plausible mechanism which includes the role of sulphur dioxide, carbon dioxide or selenium dioxide has also been described.

KEYWORDS:

Synthesis of triazoles; Physico-chemical properties