Synthesis and Biological Evaluation of Thieno Pyrimidine Derivatives

Manish Shah, Pankaj Patel and Hansa Parekh*

Department of Chemistry, Saurashtra University, Rajkot- 360 005 (India)

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ABSTRACT:

A series of substituted thiosemicarbazides have been synthesised in 54 to 67% yield, by the reaction of 4-hydrazino-6-phenylthieno [3,2-d] pyrimidine with arylisothiocyanates. The synthesised products have been screened for their antimicribial activities against several microbes.

KEYWORDS:

Biological evaluation; thieno pyrimidine; microbes