Synthesis of Quinolinyl Hydrazino Benzylidene Azobenzenes as Anti Tubercular / Anti Bacterial Agents

D. C. Tandel; C. M. Desai; Dinesh Patel; Bhavin Naik; Sunil Marjadi

Article | Open Access

Synthesis of Quinolinyl Hydrazino Benzylidene Azobenzenes as Anti Tubercular / Anti Bacterial Agents

D. C. Tandel, C. M. Desai, Dinesh Patel, Bhavin Naik and Sunil Marjadi*

Themis Medicare, GIDC, Vapi- 396 195 (India) *B.K.M. Science College, Valsad- 396 001 (India)

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ABSTRACT:

Schiff's bases obtained by condensing 2,8-dimethyl-4-quinolinyl hydrazines with 4-methoxy or 2-chloro benzaldehyde, were coupled with diazotised aryl amines giving respective azobenzenes, called Formasans, which were tested against Mycobacterium H37Rv for antitubercular activity against E. coli, B. subtilis, S. aureus and S. paratyphi B for antibacterial activity.

KEYWORDS:

Quinolinyl hydrazines; azobenzenes; formasans; antitubercular; antibacterial activity