Synthesis and Anticancer Activity of Some 1-(2′,3′-Dimethyl- 1′-Phenyl-3′-Pyrazoline-5′-One-4′-Yl)-2-Phenyl-4- (Substituted Benzylidine)-5-Imidazolinones


A. Solankee*, K. Kapadia, K. Upadhyay and J. Patel
Department of Chemistry, B.K.M. Science College, Valsad-396 001 (India)

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ABSTRACT:

Some new 1-(2',3'-dimethyl-1'-phenyl-3'-pyrazoline-5'-one-4'-yl)-2-phenyl-4-(substituted benzylidine)-5-imidazolones are prepared by refluxing the mixture of 5-oxazolone derivatives with 4-amino antipyrine in pyridine. The synthesised compounds are tested for their anticancer activity. Structures of synthesised compounds have been elucidated on the basis of their elemental analysis and spectral data.

KEYWORDS:

Anticancer activity; substituted imidazolinones


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