ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
     FacebookTwitterLinkedinMendeley

Spectrophotometric method for the determination of amorolfine

A. APARNA*, B. ANUPAMA , G. VINDYA and G. DEVALA RAO

K.V.S.R. Siddhartha College of Pharmaceutical Sciences, Siddhartha Nagar, Vijayawada - 520 010 (India).

Article Publishing History
Article Received on :
Article Accepted on :
Article Metrics
ABSTRACT:

Two simple and sensitive spectrophotometric methods have been developed for the estimation of Amorolfine (AMF) in pure and pharmaceutical dosage forms. Method A is based on oxidative coupling of the drug with 3-methyl 2-benzothiazolinone hydrazone(MBTH λmax 660 nm). The absorbance of the colored species is measured against the corresponding reagent blank. Method B is based on oxidation followed by complex formation when the drug reacts with ferric chloride and 1,10- phenanthroline (λmax 510nm) .These methods have been statistically evaluated and found to be precise and accurate.

KEYWORDS:

Spectrophotometry, Amorolfine, pharmaceutical dosage form.

Download this article as: 

Copy the following to cite this article:

APARNA A, ANUPAMA B, VINDYA G, RAO G. D. Spectrophotometric method for the determination of amorolfine. Orient J Chem 2010;26(3).


Copy the following to cite this URL:

APARNA A, ANUPAMA B, VINDYA G, RAO G. D. Spectrophotometric method for the determination of amorolfine. Orient J Chem 2010;26(3). Available from: http://www.orientjchem.org/?p=29698



Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.