Development and Validation of Spectroscopic Method for Estimation of Valacyclovir in Tablet Dosage form
M. Sugumaran* and D. Jothieswari
Adhiparasakthi College of Pharmacy, Melmaruvathur - 603 319 (India).
A simple, rapid and sensitive method has been developed for the quantitative estimation of valacyclovir hydrochloride in bulk and tablet. The wavelength 252 nm was selected for the concentration range 4-24μg/ml. The accuracy of the method was assessed by recovery studies and was found between 99.61-101.28%. The method was statistically validated for the linearly, precision, accuracy repetability. LOD, LOQ and ruggedness. The method was successfully applied for routine analysis of this drug in bulk and formulations.
KEYWORDS:Valacyclovir; UV-spectroscopy; validation and recovery
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| Copy the following to cite this article: Sugumaran M, Jothieswari D. Development and Validation of Spectroscopic Method for Estimation of Valacyclovir in Tablet Dosage form. Orient J Chem 2010;26(1). |
| Copy the following to cite this URL: Sugumaran M, Jothieswari D. Development and Validation of Spectroscopic Method for Estimation of Valacyclovir in Tablet Dosage form. Orient J Chem 2010;26(1). . Orient J Chem 2010;26(1). Available from: http://www.orientjchem.org/?p=23560 |
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