Synthesis of 6-Phenyl-1,2,3,4-Tetrahydrodibenzo [B,G] [1,8] Naphthyridines

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Substituted 6-phenyl-1,2,3,4-tetrahydrodibenzo [b,g] [1,8] naphthyridine 4 have been synthesized by the condensation of 2-amino-3-formyl-4-phenylquinoline 3 with cyclohexane in presence of acetic acid and sulphuric acid. The precursors have been obtained by the amination of 2-chloro-3-formyl-4-phenylquinoline 2 which inturn were obtained by the oxidation through prevost reaction of 2-chloro-4-phenylquinoline 2 which inturn were obtained by the oxidation through prevost reaction of 2-chloro-4-phenyl-3-vinylquinoline 1.

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