ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Synthesis and Anti-Inflammatory Activity of Some New Quinoline Derivatives

Mohammed Amir

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi–110 062 (India)

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ABSTRACT:

A of hydrazones derivatives of 6-substituted-2-chloro-3-formyl quinoline have been synthesized and evaluated for their anti-inflammatory activity. The tested compounds show 31 to 45% inhibition at 100 mg/kg dose compared to naproxen which showed 61% inhibition at 50 mg/kg dose in carrageenan induced paw edema in rats.

KEYWORDS:

Quinoline derivatives; antiinflammatory activity

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Mohammed Amir M. Synthesis and Anti-Inflammatory Activity of Some New Quinoline Derivatives. Orient J Chem 2001;17(2).


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Mohammed Amir M. Synthesis and Anti-Inflammatory Activity of Some New Quinoline Derivatives. Orient J Chem 2001;17(2).Available from: http://www.orientjchem.org/?p=16116



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