The Role of Atom Shadow on Sorbitol Molecules to Heal Diabetic Diseases

Sorbitol has a low calorie value, this is due to the presence of a pair of O-H free electrons on the sorbitol molecule. The pair of free electrons can be removed by the Tunnel method (through the shadow of the sorbitol container). Sorbitol which has lost a pair of free electrons from the O-H group is called sorbitol switching. The instrument used to prove the release of a pair of free electrons in the O-H group is to use FTIR and clinical trials conducted on mice given sorbitol to prove the effectiveness between sorbitol and sorbitol switching. The results show that sorbitol switching is able to maintain the stability of blood sugar levels in the body of mice and can reduce blood sugar levels.


INTRODUCTION
The consumption of sucrose as a food sweetener is now being replaced and reduced by its use. Sugar substitutes must meet the requirements, namely that they must have a sweet taste, are not toxic, are not expensive, cannot be shared by dental plaque bacteria, have calories, besides that they must also be able to be done industrially. Of all these requirements, a good sugar substitute is derived from the sugar alcohol group 1 . Sorbitol (C 6 H 14 O 6 ) comes from the sugar alcohol group. Sugar alcohol is the result of reduction of glucose in which all the oxygen atoms in a simple sugar alcohol molecule are present in the form of a hydroxyl group, synonymous with polyhydric alcohol (polyols) 2 . Polyols can be divided into two, namely acyclic polyols and cyclic polyols. Sorbitol belongs to the acyclic polyols group with six carbon chains 3 and has the advantage, among others, that it is not cariogenic 4 .
Sorbitol is included in the unique sugar alcohol group, namely sugar alcohols do not have a carbonyl group in the chain. This fact makes sugar alcohols less chemically reactive than sugars which have aldose and ketose bonds and thus participate less in the formation of acids in dental plaque 5,10 . Sorbitol is a glucose-derived sugar alcohol or polyol sweetener. This sweetener is water soluble and is found in many fruits and vegetables 6,9 . Sorbitol is a low calorie sweetener. When compared to sugar, sorbitol has 35% lower calories. One gram of sugar provides 4 calories.Meanwhile, one gram of sorbitol provides only 2.6 calories. Because of its low calorie content, sorbitol is often incorporated into multi-industrial products, including pharmaceutical products, sugar-free processed foods, and oral health products. These sweeteners are also added to processed products to add flavor, improve texture and retain moisture 7,8 .
Sorbitol can be used as a substitute for sucrose in people with diabetes. The caloric value of foods containing sorbitol is as high as sugar, but the sweetness is only about 60 percent of the sweetness of sucrose. The disadvantage of sorbitol is that when used in excessive amounts it can cause diarrhea. Sorbitol is a sugar that is absorbed very little by the small intestine, so that sorbitol will enter the large intestine directly and can support diarrhea and flatulence 11 . Sorbitol is quite safe to use as a sugar substitute in people with diabetes mellitus, because its absorption is slower than glucose. This slow absorption will automatically reduce the degree of drastic increase in blood glucose and insulin response. Low calories are also in accordance with the target of weight control in diabetes mellitus patients. For this purpose sorbitol is widely used to make low-calorie food products such as sugar-free candy, chewing gum (usually mint flavor), confectionery industry, bread and chocolate sweeteners, and frozen food sweeteners 12 .
The atoms in a molecule have a shadow (soul). The nature of the true atom and its shadow can show different physical and chemical properties. We can see this phenomenon from the XRD analysis of graphene which shows different crystallinity 15 . Therefore, in this paper, we conducted a study to prove the phenomenon of soul atoms and their application in lowering blood sugar levels by comparing the effectiveness of true sorbitol with shadow sorbitol.

Materials and Instrumentations
The materials used in this study were kerosene, sorbitol, charcoal. FT-IR analysis using a Shimadzu IR Prestige-21 and clinical testing of blood sugar levels in mice using a glucometer measuring strips.

Methods
250 mL of sorbitol, put into plastic containers that have been cleaned, then pour the kerosene into a glass plate. Put the plastic containers containing sorbitol on a glass plate that has been filled with kerosene and place the charcoal on the bottom of a wooden cabinet that has a neon lamp inside. Turn on the fluorescent lights, and let the exposure occur for seven days in a closed state. After seven days, sorbitol switching is obtained which will be analyzed by FTIR and clinical test on mice.

FTIR Analysis
Sorbitol switching is produced due to the irradiation of fluorescent lamps which makes the sorbitol contained in the container produces a shadow which will be absorbed by the adsorbent, the charcoal found at the bottom of the wooden cabinet. The irradiation produces shadows, and causes the release of free electrons in the O-H group on sorbitol. The release of free electrons in the sorbitol molecule is called sorbitol switching. The evidence that shows that the sorbitol molecule has released a pair of electrons from the O-H group can be seen from the difference in the FTIR spectrum shown in Figure 1. In Fig. 1, there is a difference in %T absorbed by the sorbitol and sorbitol switching molecules at a wavelength of 1408 cm -1 . It can be seen that the %T in the sorbitol molecule is 59% while in the sorbitol switching molecule is 57.5%. This reduction in %T could explain the indication of the release of a pair of free electrons from sorbitol.
The intensity drops because a pair of free electrons in the O-H group has been absorbed by the shadow of the atom.

Clinical test for mice
Clinical tests of sorbitol and sorbitol switching are performed on mice weighing about 135-160 g and blood sugar levels before being given alloxan is 89-101 mg/dL on the first day. Treatment of alloxan, sorbitol, and sorbitol switching as well as measurement of blood sugar levels before giving alloxan, sorbitol, and sorbitol switching can be seen in Figure 2.
From Fig. 4, it can be seen that the mice that had not been given alloxan showed a relatively stable average blood sugar level and fluctuated from the first day to the last day of observation, with an average blood sugar level of 107 mg/dL. Whereas in Fig. 5, when the mice were treated with alloxan, there was a spike in blood sugar increases from the first day to the second day and was relatively stable on the third to the last day of observation with an average blood sugar level of 231 mg/dL and a decrease in blood sugar levels the average from the second day to the eighteenth day was 8%.  the release of calcium ions from the mitochondria which results in disrupted cell oxidation processes 13 . The release of calcium ions from the mitochondria results in a disruption of homeostasis which is the beginning of cell death. With the destruction of the β cells of the islets of Langerhans, the body will lose insulin absolutely so it is very dependent on insulin from outside the body 14 . Figure 6 is a graph showing the treatment of mice treated with sorbitol. The spike in the increase in blood sugar occurred on the first day to the tenth day reaching the highest peak with blood sugar levels of 247 for each mouse; 575; 348; 352; 260 mg/dL. On the eleventh day, there was a decrease in blood sugar levels until the last day of observation and the average decrease was 70%.
Meanwhile, Fig. 7 shows the treatment of mice given sorbitol switching. Similar to the treatment of sorbitol, sorbitol switching which was tested on mice raised blood sugar levels on the second to the tenth day, what was different was that sorbitol switching raised the average blood sugar level to a level of 307 mg/dL, not too high compared to sorbitol. Decrease in average blood sugar levels with sorbitol switching treatment reached 74%.
From Fig. 6 and 7 it can be seen that the treatment of sorbitol switching can maintain the stability of blood sugar levels and is more effective in reducing blood sugar levels than sorbitol. This is because the switching sorbitol which has lost a pair of electrons from the O-H group results in a reduced calorific value so that it can lower blood sugar levels compared to sorbitol and this also shows that sorbitol switching is an atomic image of the sorbitol molecule.

CONCLUSION
Based on the results of the research conducted, it can be concluded that sorbitol has lost free electrons adsorbed by atomic shadows, resulting in sorbitol switching. This can be proven from the decrease in %T sorbitol switching in the FTIR analysis results. The results of clinical trials proved that sorbitol switching was able to maintain the stability of blood sugar levels and was able to reduce blood sugar levels in mice.